Orbital mass as first presentation of metastatic p16-positive oropharyngeal squamous cell carcinoma

J. Corbett, D. Wilke, J. Trites, N. Lamond

Abstract


We describe a case in which a 67-year-old man was diagnosed with a metastatic recurrence of p16-positive oropharyngeal squamous cell carcinoma after presenting with a medial orbital mass in the region of the nasolacrimal apparatus. A review of the literature revealed that metastasis to the orbit from any malignancy is an uncommon occurrence, and no cases of p16-positive oropharyngeal squamous cell carcinoma have previously been reported. Our case highlights the importance of maintaining a high index of suspicion during surveillance visits with such patients.

Keywords


Human papillomavirus; oropharyngeal squamous cell carcinoma; p16-positive disease; distant metastases; orbital metastases

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DOI: http://dx.doi.org/10.3747/co.24.3523






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ISSN: 1198-0052 (Print) ISSN: 1718-7729 (Online)